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 project deals with understanding genomic, microbiological, and ecological bases of invasiveness and adaptive capacities of mosquitoes to temperate vs tropical regions, in the context of global changes and risk of emerging vector-borne diseases in Europe. The goal is to use genotype x environment interaction approach to investigate the effect of host genome and its microbiome on mosquito invasion/adaptation and vector capacity by comparing native, founder, and colonizing field populations, taking into account anthropogenic activities (pollution, land use etc.) and global changes (climates, trade etc.). Comparative studies concern wild mosquito populations collected from different continents in natural (less anthropogenic) to manmade (moderate to highly anthropogenic) environments. In parallel, experimental evolution will be performed in innovative experimental infrastructure, to simulate particular ecological perturbations at “semi-field conditions” to test hypotheses on genetic and ecological forces driving evolution and biological invasion and adaptation with high impact on disease transmission potential.

GC-INVAMOFECT aims to address the following questions in relation to occurrence of two invasive mosquitoes species (Aedes albopictus and Ochlerotatus japonicus), their associated microbiota, and infectious risks in Europe:

  • i.- What are the current niche occupations of the two mosquito invasive species in Europe under climate change and anthropogenic pressure?
  • ii.- What are the potential functions and the diversity of the microbiota (symbionts and pathogens) associated with invasive wild mosquitoes in Europe?
  • iii.- Do microbes facilitate or constrain adaptation to a changing environment (temperature, anthropogenic activities)?
  • iv.- How pathogens-symbionts interactions evolve in European invasive mosquitoes?
  • v.- Can we establish correlations between mosquito spreading, microbiota content, ecological and high-level human activities to guide coherent policy vector control and biodiversity conservation in articulation with human and animal health?  

 

        

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